Head to Head
| England - Premier League 2 | 2017/08/14 18:00 | Southampton U21 v Reading U21 | W | 4-0 |
Home History
| England - Premier League 2 | 2023/09/22 18:00 | West Ham U21 v Southampton U21 | D | 3-3 |
| England - Premier League 2 | 2023/09/01 14:00 | Fulham U21 v Southampton U21 | L | 5-1 |
| England - Premier League 2 | 2023/08/25 17:00 | Southampton U21 v Liverpool U21 | L | 0-3 |
| England - Premier League 2 | 2023/08/18 18:00 | Southampton U21 v Aston Villa U21 | W | 4-2 |
| England - Premier League 2 | 2023/08/13 11:30 | Newcastle U21 v Southampton U21 | L | 5-3 |
| England - Premier League 2 | 2023/04/23 13:00 | Norwich U21 v Southampton U21 | W | 2-5 |
| England - Premier League 2 | 2023/04/14 18:00 | Southampton U21 v Stoke U21 | W | 2-0 |
| England - Premier League 2 | 2023/03/31 18:00 | Derby U21 v Southampton U21 | W | 1-3 |
Away History
| England - Premier League 2 | 2023/09/22 18:00 | Reading U21 v Leeds U21 | W | 3-2 |
| England - U21 Premier League Cup | 2023/09/11 18:00 | Reading U21 v Blackburn U21 | L | 1-2 |
| England - Premier League 2 | 2023/09/03 11:00 | Arsenal U21 v Reading U21 | L | 3-0 |
| England - Premier League 2 | 2023/08/25 18:00 | Reading U21 v Newcastle U21 | W | 1-0 |
| England - Premier League 2 | 2023/08/20 12:00 | Reading U21 v Crystal Palace U21 | W | 2-0 |
| England - Premier League 2 | 2023/08/14 18:00 | Stoke U21 v Reading U21 | W | 0-2 |
| England - Development League 2 | 2023/05/05 12:00 | Reading U21 v Barnsley U21 | L | 0-3 |
| England - Development League 2 | 2023/05/01 13:00 | Birmingham U21 v Reading U21 | D | 1-1 |